Is CBD Safe For Children?

Is CBD Safe For Children?

Many parents who are using CBD regularly have been reporting that it has successfully treated several ailments for them, from anxiety to pain relief, acne and many more. 

But what about giving CBD to kids? Is CBD safe for children? In this article, we will look to examine the evidence associated with the safety and therapeutic benefits of CBD use in children. 

How Is CBD Different From Marijuana?

Cannabis holds over 100 different chemicals known as cannabinoids. The primary psychoactive element in cannabis is delta-9-tetrahydrocannabinol (THC), which creates euphoria, shifts in perception and mood, as well as provides an improvement in appetite. In contrast, CBD solely offers a level of sedation, without the psychoactive results connected with THC.

Marijuana is made of the dried petals, stems, and leaves of the female cannabis plant and holds between 3% – 20% THC. Various subspecies contain varying ratios of THC to CBD, with the most significant ratios in Cannabis sativa, and the weakest in Cannabis indica. 

“Hemp” is the terminology applied to distinguish varieties of cannabis holding 0.3% or less of THC and is the base of most CBD stocks accessible commercially. 

THC works by binding to 2 cell membrane receptors, named the cannabinoid type 1 (CB1) receptor and type 2 (CB2) receptor. Cannabinoid type 1 receptors are primarily concentrated in brain tissues, and CB2 receptors are located in immune and hematopoietic cells. Through its impacts on these receptors, THC influences pain, anxiety, perception, memory, learning, and motor control.

On the other hand, CBD does not influence CB1 and CB2 receptors and applies its sedative nature by altering numerous other neurotransmitters. It also has been illustrated to decrease the euphoric effects of THC by inhibiting its influence on the CB1 and CB2 receptors and changing the metabolism of THC.

The Evidence For CBD Health Benefits

CBD is being  praised for its benefits in treating various health issues, but the most reliable scientific testimony is for its potency in treating some of the most brutal childhood epilepsy syndromes, such as Dravet syndrome and Lennox-Gastaut syndrome that do not generally respond to anti seizure remedies. In various studies, CBD has demonstrated the effectiveness of reducing the number of seizures, and in some cases, even stopping them entirely. The Food and Drug Administration (FDA) has already approved cannabis-derived medicine, the cannabidiol drug Epidiolex, which can help reduce symptoms of epilepsy. 

Another study published in JAMA Neurology approved prior study results describing the effectiveness of this treatment for Dravet syndrome at a dosage of 20 mg per kg per day. The trial, which involved 199 patients aged between 2 and 18 with a diagnosis of Dravet syndrome, recorded that the 10mg dose might be equally as efficient as the 20mg dose. Experts observed that those who took 10mg experienced seizure declines of 49% contrasted with 46% decrease in those who took 20mg and a 27% decrease for those who took a placebo.

The Epidiolex examinations present evidence that CBD in proper dosages can be effective for seizures in children diagnosed with Dravet syndrome and Lennox-Gastaut syndrome. Epidiolex may also confirm to be a valuable antiepileptic treatment for refractory seizures in additional conditions. 

With some of the benefits of cannabidiol already recognized, Pharmaceuticals are continually seeking the approval from FDA for the treatment of patients who have multiple sclerosis, autism, schizophrenia, spinal cord spasticity, and PTSD (post-traumatic stress disorder).

There are currently a significant amount of ongoing clinical trials concerning the use of CBD products for conditions that involve various conditions such as refractory seizures and anxiety, feeding the hope that soon, we will have more clinically approved data upon which to base the evidence of CBD health benefits. 

How Safe Is CBD For Children?

A report from the World Health Organization affirms that in humans, CBD exhibits no effects indicative of any abuse or dependence potential. The report goes on to state that, to date, there is no evidence of public health-related problems connected with the application of pure CBD.

However, if you are new to using CBD or if you are uncertain if CBD is right for you and your family, do make sure that you take advice from a medical practitioner or an expert in the CBD field. A good starting point would be your family doctor; however, you must bear in mind that many medical professionals are still unfamiliar with CBD products and there is still a large degree of stigma attached to the subject. Equally, you may wish to conduct independent research online or perhaps look to consult with long-standing experts and reputable advocates in the CBD industry.    

It is also sensible to always apply caution when purchasing CBD online.  There are many reputable CBD providers online, but not all brands are bound by appropriate ethical standards, mainly due to the lack of regulation in the industry. Therefore, you should conduct relevant research and make sure that the products you purchase contain the advertised dosages. Only purchase CBD online from a reputable and ethical brand, and remember that the size of the company does not necessarily indicate their commitment to prioritization of quality. Never purchase a CBD product without making sure that you have read the third-party lab report. 

CBD Edibles For Children To Try 

If you are looking to introduce CBD in your family lifestyle, you might wish to begin by introducing products in sweetened forms. Children are likely to tolerate these much better than oil droppers.

Products, such as Bolder Caramels  are made of hemp oil-infused coconut milk, palm sugar, sea salt and phytochemical-rich extracted hemp oil. The delicious artisan-crafted caramels offer a delicious way to enjoy CBD. 

Healing Properties of Cannabinoids

Healing Properties of Cannabinoids

With so many illnesses as a concern in the forefront of people’s mind, many are trying to find the best way to help themselves. The healing properties of cannabinoids have been recognized through hearsay for generations, and the research community is now scientifically understanding why people use cannabinoid infused product to treat illness symptoms.

Nausea and Vomiting

When you get sick, your body tries to get rid of whatever is ailing you in any way possible. Studies show significant healing properties of cannabinoids, such as CBD, on illness symptoms such as nausea and vomiting. Cannabinoids have been shown to have a significant anti-emetic effect, referring to suppression of nausea and prevention of vomiting.

CBD has this affect because it interacts with the serotonin receptors in your body, both in the brain and stomach. It helps to block the nausea symptoms and can offer relief for those feeling unwell. This affect is not only for those with a bacterial or viral illness, but other related conditions. Many people also experience anxiety and stress through stomach problems. CBD not only helps to alleviate stomach ailments, but can also help manage the contributing factors to this feeling.

CBD’s interaction with the CB1 receptors in the body means that it could help alleviate the feeling of nausea and ultimately vomiting by allowing your body to regulate these responses. Medical Marijuana is commonly used for those with conditions that have nausea associated with it, such as those going through cancer treatment. Research has seen great results in the effects of CBD in regulating this physiological response.

Immune System

The endocannabinoid system helps to regulate a whole host of functions in the body. One of which is the immune system. The immune system functions to keep your body safe from foreign invaders. It recognizes when something is harmful or does not belong and works to fight it. Sometimes, the immune system needs a boost, especially when faced with a challenge it has not previously encountered.

Research has shown the potential for CBD to help regulate and boost the immune system. While CBD can aid in inflammatory reactions, helping the immune response, THC can be an immunosuppressant. This means that THC can be beneficial for those with autoimmune diseases which show an excess of inflammation. However, THC might hurt someone with a healthy immune system by suppressing its response.

CBD can give the immune system a leg up by allowing it to operate optimally. While supporting all of the other systems in the body, this balance allows for prime functioning of the immune system. Your body is not working as hard to maintain homeostasis, therefore it can work the way it needs to in order to protect itself.

Research has shown that CBD might be able to help with a whole host of conditions. If you find yourself feeling under the weather, consider a hemp plant extract to aid you.

As always, consult with your doctor if you have any concerns about integrating CBD into your life, especially if you are being treated for a medical condition. If you have any questions call us here at Revexia: (970) 443-1603.

Women in Cannabis

Women in Cannabis

In light of International Women’s Day celebrated this past Sunday, March 8, we at Revexia felt inspired to bring light to the innovative group of women who have fundamentally impacted the cannabis community. This day was brought into a national holiday given the lack of rights and resources women were faced with for centuries. Exploring the history of this holiday shines light on the sheer persistence these women in cannabis have prevailed through to become the leaders they are today.

History Leading to International Women’s Day

Rhetoric surrounding change started sweeping the community of women back in the early 1900s. Women were legally barred from voting and education, had sparse access to economic opportunity as well as voice in the political realm, and were openly looked down upon. In response, a group of men and women (mostly women) gathered and drafted a declaration inserting women into legal memorandum asserting their deserved position in society. A few decades later, International Women’s Day was established in 1913, but was not recognized by the United Nations in 1975.

Why Women Are So Dominant in Cannabis Industry

Flash forward to 2012. Colorado and Washington propelled the cannabis industry into the mainstream marketplace by legalizing recreational cannabis usage, and women saw this as their time to shine. Because this trade was the first of its kind, women found they had the opportunity to shape the industry, not fit into the previously established patriarchal confines in the outside-of-cannabis business world.

There are numerous organizations dedicated to empowerment of women in the cannabis community, such as Women Grow, Illinois Women in Cannabis, and Ellementa. To bring these and others together, along with women not having capacity to belong to such an organization due to geographical limitations, a conference was held in Las Vegas late 2019 called the Women of Cannabis Conference. The possibility alone for an international conference to take place surrounding the sheer impact women have had in the industry is novel and exciting for female cannabis entrepreneurs.

Powerful Women Making an Impact

Karson Humiston, Owner and CEO of Vangst

Vangst has been an industry game changer. Noticing a gap in the cannabis industry, Karson Humiston created a platform that connects cannabis industry workers with careers through key players in the industry. A first of its kind, Karson Humiston fundamentally impacted the cannabis industry forever.

Dahlia Mertens, Owner of Mary Jane’s Medicinals

Dahlia Mertens founded Mary Jane Medicinals in response to her own personal introduction to cannabis infused oil. A trained massage therapist, she recognizes the importance of cannabis in self-care routines. Mary Jane Medicinals is one of the leading topical companies in the U.S. topical market.

Mara Gordon, Co-Founder and Chief Process Engineer of The Oil Plant

A woman grounded in science, Mara Gordon has brought cannabis into the mainstream through a medical lens. Her company Aunt Zelda provides contaminant-free high quality cannabis infused products in proper dosages and tailored to the individual patient. She also is a key advocate in the industry, having given a Ted Talk and participating in numerous documentaries to help break the stigma and misinformation surrounding cannabis.

Women Near and Dear to Us at Revexia

We also want to take a minute to thank the women on our team who make all of this possible. Although our staff may be small in numbers, our gratitude for the work these women complete each day is massive. Similarly, we extend our deepest appreciation for our customers who find relief from the products we believe in so deeply. Without each piece of this puzzle, Revexia would not be able to be where we are today.

CBD Interaction with Autism

CBD Interaction with Autism

CBD and Autism

People who have autism are generally faced with the reality of numerous medications for a plethora of different accompanying issues. Many parents and people who have autism have turned to CBD as a plant-based alternative to the pharmaceuticals they are prescribed. With CBD products being a newer mainstream concept, research is minimal thus far. With an eye towards education, we have explored and compiled all the information we could find surrounding CBD interaction with autism.

As there is no medication that treats or cures autism, similarly CBD doesn’t treat autism itself, but studies show it can help to alleviate the symptoms that accompany this condition.

Autism

Autism, or autism spectrum disorder (ASD), refers to the range of conditions that affect people through their social skills and communication, and is often characterized by repetitive behaviors and speech and nonverbal communication. This condition is a spectrum disorder, meaning that individuals with ASD can range from mild or moderate symptoms to more severe, requiring constant support.

Areas commonly affected by this condition include gastrointestinal disorders, seizures and sleep disorders. Anxiety, depression and attention deficits are usually present.

People with autism typically have a long list of daily medications, which can cause more problems than they solve. This lends itself to more parents and caregivers turning to CBD for alternative treatment, exploring CBD interaction with autism.

Mental Health

Anxiety and depression are commonalities seen in those diagnosed with autism. Many are put on mood stabilizers to combat these symptoms, which have countless negative side effects.

As of late, cannabis has been claimed as a top contributor for easing anxiety amongst the masses, and recent research has started to back these claims. CB1 receptors have been among the neurological transmitters targeted by anti-anxiety medication, as they play a key role in regulatory systems. Cannabinoids such as CBD function as the direct agonist to these receptors, creating an exciting pathway to aiding in this issue.

A study completed in Israel with children with autism around the age 11 concluded that 47% of these patients had lessened anxiety related symptoms. This is significant because it gives hope to those relying on harsh medications that have previously been their only option.

Another study completed with adults who have anxiety showed just under 80% of patients reported improvement in their anxiety levels after just two months of treatment using this cannabinoid.

Communication is a cornerstone concern for individuals that have autism. Verbal and nonverbal communication is commonly targeted in therapies for autism spectrum disorder. These issues can be directly related to anxiety, therefore affected by the same CB1 receptors that CBD has impact on. In a study completed in Brazil on 18 patients diagnosed with autism, communication was reportedly one of the strongest improvement areas.

Health Problems

People who have autism suffer from numerous health problems associated with this condition. An autism diagnosis is commonly synonymous with gastrointestinal problems, seizures and sleep disorders, among others.

As mentioned in our previous blog, cannabinoids like CBD interact with CB2 receptors to help regulate our body’s homeostasis. CBD interacts with regulatory function of the immune system, which can affect diseases with gastrointestinal symptoms. Studies show that a high CBD intake perpetuates regulation of these functions, decreasing symptoms that accompany gastrointestinal problems.

Seizures are also common in patients with autism. Many studies indicate a positive response from individuals with seizure disorders, with one medication currently on the market derived from cannabis.  Seizures occur due to electrical dissonance in one’s brain. CBD works to decrease the amount of excitatory neurotransmitters released to the brain, which lessons possible risk for a seizure. Understanding this concept, CBD has been worked into the pharmaceutical industry through Epidiolex, the first ever CBD drug approved by the FDA. This was specifically designed to treat people with treatment resistant epilepsy disorders, and the success rates quickly showed substantial reduction in seizures.

Individuals with autism spectrum disorder can be plagued by sleep disorders and dysregulated sleep patterns. Hyperactivity and aggression can stem from these sleep related issues. CBD can help mitigate this through affinity towards the CB1 receptors within our systems help to regulate proper sleep.  In a study conducted in Israel, children with autism were given CBD to treat comorbid symptoms of the condition. Results showed that over 70% of the patients studied had improved sleep habits.

CBD has been touted as a cannabinoid assisting in mental health therapy and specific health issues through anecdotal evidence for a while. The symptoms of autism are directly in line with the commonalities CBD has been claimed to treat. This lends itself to a hypothesis and a hope that alternative treatment for autism spectrum disorder is on the horizon.

Recent research has pointed in the positive direction for those growing wary of the multitude of pharmaceutical drugs associated with an autism diagnosis. As always, consult your doctor regarding CBD interaction with autism before including CBD treatment into your daily regimen when treating symptoms of autism.

CBD and Digestive Health

CBD and Digestive Health

CBD and Digestive Health

Digestive problems seem to be running rampant in today’s health community. Diagnoses like IBD, Crone’s, and leaky gut are becoming more prevalent. Many individuals have seemed to find relief from utilizing CBD in their daily routine, many finding correlation between CBD and digestive health.

The Endocannabinoid system in our bodies helps to regulate a whole host of functions, one of which is the immune system. Our first line of immune defense is our digestive tract, primarily the gut. This is why when we get sick we tend to notice gastrointestinal issues first. Many people with autoimmune diseases not primarily characterized with digestive problems still experience gastrointestinal discomfort. This is because their immune system is not functioning the way it should, thus their gut is not happy with them.

The Immune System

Cannabinoids help to regulate the immune system by interacting with CB2 receptors in our bodies. They activate cannabinoid receptors that aid in homeostasis, making sure our bodies are responding appropriately to different situations. CB2 receptors are found throughout the body, with a great concentration in the gastrointestinal system, here they work to limit unnecessary immune responses. This does not mean that cannabinoids suppress the immune system, it means they allow the immune system to function better, recognizing when immune defense is actually needed and when it is not.

Diseases like IBD and Crone’s are situations in which the immune system in the gut is not working correctly and attacks the body as a foreign body or malicious entity. Those suffering with this disease experience gastrointestinal discomfort and food sensitivities. It is not known exactly what causes this immune system malfunction, but current research indicates it might have a connection with the endocannabinoid system. This would make sense because of the endocannabinoid system’s great influence on the immune system.

The Research

In a study done in 2011, a number of patients with IBD that was resistant to treatment showed marked improvement in symptoms following an introduction of CBD oil into their daily regimen. It is unclear whether or not this was merely based on cannabinoids helping with the symptoms or the underlying issue causing them. However, this is promising to those who experience frustration without relief of their disease.

The most significant improvement seen is in the quality of life. For those with chronic illness, living a normal life with the disease is the hardest part. With limited options for treatment of these inflammatory conditions, CBD offers a viable option for relief. With legalization of cannabinoids from hemp and medical marijuana, more and more patients are turning to alternative treatments.

Crone’s disease is an autoimmune disease that is characterized by inflammation of the digestive tract. Those with this disease often suffer gastrointestinal discomfort and pain. Food sensitivities accompany this illness and often lead to extreme weight loss. In a study that compared the use of CBD to a placebo, the group that consumed cannabis showed more improvement in their symptoms. It is important to note that these results are in comparison to a placebo treatment. However, when considering the alternative medications to Crone’s and their side effects CBD might be a more appealing option.
In many cases, steroids are used to treat chronic inflammation, and when used long term they can cause diabetes, high blood pressure, and higher risks of infection.

While there is limited evidence that shows the validity of actual treatment of diseases using cannabinoids, the improvement in symptoms is enough to give hope. As with any medical decision, be sure to consult with your doctor if you are considering adding CBD to your diet. Consider any other medications you are taking as some are metabolized in a way that is not compatible with CBD.

For any questions or to try CBD out for yourself feel free to call us here at Revexia: (970) 449-1603, or stop by our storefront located at 1724 Topaz Drive, Loveland, CO 80537.