CBD and Digestive Health

CBD and Digestive Health

CBD and Digestive Health

Digestive problems seem to be running rampant in today’s health community. Diagnoses like IBD, Crone’s, and leaky gut are becoming more prevalent. Many individuals have seemed to find relief from utilizing CBD in their daily routine, many finding correlation between CBD and digestive health.

The Endocannabinoid system in our bodies helps to regulate a whole host of functions, one of which is the immune system. Our first line of immune defense is our digestive tract, primarily the gut. This is why when we get sick we tend to notice gastrointestinal issues first. Many people with autoimmune diseases not primarily characterized with digestive problems still experience gastrointestinal discomfort. This is because their immune system is not functioning the way it should, thus their gut is not happy with them.

The Immune System

Cannabinoids help to regulate the immune system by interacting with CB2 receptors in our bodies. They activate cannabinoid receptors that aid in homeostasis, making sure our bodies are responding appropriately to different situations. CB2 receptors are found throughout the body, with a great concentration in the gastrointestinal system, here they work to limit unnecessary immune responses. This does not mean that cannabinoids suppress the immune system, it means they allow the immune system to function better, recognizing when immune defense is actually needed and when it is not.

Diseases like IBD and Crone’s are situations in which the immune system in the gut is not working correctly and attacks the body as a foreign body or malicious entity. Those suffering with this disease experience gastrointestinal discomfort and food sensitivities. It is not known exactly what causes this immune system malfunction, but current research indicates it might have a connection with the endocannabinoid system. This would make sense because of the endocannabinoid system’s great influence on the immune system.

The Research

In a study done in 2011, a number of patients with IBD that was resistant to treatment showed marked improvement in symptoms following an introduction of CBD oil into their daily regimen. It is unclear whether or not this was merely based on cannabinoids helping with the symptoms or the underlying issue causing them. However, this is promising to those who experience frustration without relief of their disease.

The most significant improvement seen is in the quality of life. For those with chronic illness, living a normal life with the disease is the hardest part. With limited options for treatment of these inflammatory conditions, CBD offers a viable option for relief. With legalization of cannabinoids from hemp and medical marijuana, more and more patients are turning to alternative treatments.

Crone’s disease is an autoimmune disease that is characterized by inflammation of the digestive tract. Those with this disease often suffer gastrointestinal discomfort and pain. Food sensitivities accompany this illness and often lead to extreme weight loss. In a study that compared the use of CBD to a placebo, the group that consumed cannabis showed more improvement in their symptoms. It is important to note that these results are in comparison to a placebo treatment. However, when considering the alternative medications to Crone’s and their side effects CBD might be a more appealing option.
In many cases, steroids are used to treat chronic inflammation, and when used long term they can cause diabetes, high blood pressure, and higher risks of infection.

While there is limited evidence that shows the validity of actual treatment of diseases using cannabinoids, the improvement in symptoms is enough to give hope. As with any medical decision, be sure to consult with your doctor if you are considering adding CBD to your diet. Consider any other medications you are taking as some are metabolized in a way that is not compatible with CBD.

For any questions or to try CBD out for yourself feel free to call us here at Revexia: (970) 449-1603, or stop by our storefront located at 1724 Topaz Drive, Loveland, CO 80537.

The Endocannabinoid Deficiency Theory Explained

The Endocannabinoid Deficiency Theory Explained

Endocannabinoid Deficiency Theory

In our previous post, we touched on the endocannabinoid system and how this neurological network works within our bodies to maintain systematic homeostasis. Cannabinoids work with CB1 and CB2 receptors to aid in regulatory functions concerning inflammation, immune response, metabolic performance, as well as a host of other operations within the human body. As an expansion on this topic, it is important to discuss endocannabinoid deficiency theory in relation to the many health claims that are tied to cannabinoids and CBD use. As always, first and foremost, any health related decisions should be discussed with a doctor, especially if you are being treated with medication for any condition. There are certain enzymes within the body that render CBD incompatible for use with certain prescription medication.

We here at Revexia do the digging in order to have the knowledge to offer insight into questions you might have regarding if CBD is right for you.

What is clinical endocannabinoid deficiency?

Clinical endocannabinoid deficiency theory is a new horizon in CBD research; it might hold the key to unanswered conditions such as autoimmune disease, fibromyalgia, and other widespread systematic disorders.

This theory was first introduced in 2001 and highlights the neurological function, or dysfunction of the cannabinoid receptors in the body. The belief is that a lack of endocannabinoid production in the body, or ineffective receptors contribute to an imbalance in the body. This leads to an ineffective or over reactive immune system, or hyperactive inflammatory response. Current studies examine the function of endocannabinoids in patients with conditions like irritable bowel syndrome and migraines, as well as psychological conditions like anxiety and post-traumatic stress disorder. From the limited studies that have been conducted, there is an indication that introduction of a CBD regimen could be helpful in these cases.

Why does this matter?

Because research has seen so many different health conditions responding favorably to CBD treatment, medical professionals hypothesize that endocannabinoid deficiency could be the underlying commonality. Cannabinoids are unique in that they do not treat diseases themselves; rather they activate regulatory systems in the body that might not be working the way they should. The hypothesis is that these hard to treat diseases could all be a product of some kind of deficiency, merely manifesting itself in different ways.

Neurotransmitter deficiencies are cited as the cause for many diseases such as Parkinson’s, Alzheimer’s, and depression. Science has identified the presence of a chemical imbalance in these conditions, marked by a either a lack of chemicals or hormones, or a failure of the receptors that utilize them.

Because the endocannabinoid system works in areas like inflammation, immunity, and cell function, it naturally fits the attributes of autoimmune diseases. Endocannabinoid deficiency could have the ability to explain the pathology behind functional disorders.  In a study published in 2004 by Neuroendocrinology Letters, endocannabinoid deficiency theory is considered provable, but requires extensive research.

It is already apparent through the few studies that have been done so far that cannabinoids have some kind of impact on many systems in the body. Many have claimed overwhelmingly positive results from CBD use. The discovery of the endocannabinoid system itself was impactful in understanding systematic function. However, what remains to be researched and uncovered is if endocannabinoid deficiency theory can be substantiated as an explanation for so many unexplained disorders.

It is clear however, that this is an avenue that should be explored further, for the sake of so many who face diseases that cannot be solved by current traditional medicine.


If you are interested in trying CBD or just want more information about the endocannabinoid system, feel free to call Revexia anytime at (970) 449-1603, or stop by our storefront at 1724 Topaz Dr. in Loveland.

CBD Product Preview: JuanaShot

CBD Product Preview: JuanaShot

“JuanaShot is just what you think it is.  …A great tasting, HIGH IMPACT addition to the Revexia Product Family.”

New Product Alert

Revexia has been working hard on our newest product launch called the JuanaShot. 

The JuanaShot is a one ounce bottle containing 50 milligrams of CBD in each bottle, with four servings. This sweet little drink can be consumed directly or mixed into your favorite drink. 

Eager to deliver the public a quick and safe CBD product, the JuanaShot was created as a quick delivery system of CBD relief whilst proving to be tasteful and subtle. Because this product is a drink, it is absorbed sublingually, or through the glands in your mouth. As the fastest cannabinoid delivery method, JuanaShot is meant for fast-acting relief.

And of course, the JuanaShot will always come with a Certification of Analysis (COA), so you can always rest assured you understand exactly what is going into your body. 



What is the Endocannabinoid System?

What is the Endocannabinoid System?

What is the endocannabinoid system?

When exploring CBD it is important to understand its biological function and how the compound interacts with the human systems. Many companies and researchers tout CBD as a claimed treatment for many diseases and conditions. However, does the everyday individual know exactly how CBD works in their body and how taking it will affect them? Understanding the endocannabinoid system is important for anyone considering adding CBD to their life.

That sounds fake.

When exploring the function of CBD we hear about this lofty thing called the endocannabinoid system. It seems hard to believe that there is a system in our bodies that is named after a recently popularized and controversial substance. Where is it? Moreover, why is CBD a miracle substance that interacts with it so well?

In an effort to do some myth busting, we have found information that is vital to the understanding of the endocannabinoid system and why CBD plays such an important role in understanding our body’s biological function.

The endocannabinoid system was discovered in 1988.

Until this point, research had been focused on cannabinoids themselves, their chemical structure and their properties. It was not until scientists discovered cannabinoid receptors in the brain of an animal that the scientific community established a substantial connection between cannabinoids and the function of the human body.

In the 1990’s scientists were able to identify endocannabinoids that were organically produced in our cells. The endocannabinoid system is a network of receptors within the neurological pathways of the human body. These receptors are activated by the presence of naturally occurring endocannabinoids produced in our cells. Research shows that these receptors play a huge role in maintaining cellular homeostasis. They affect inflammatory response systems, immune function, metabolism, and so much more.

There are two well-known cannabinoid receptors.

The CB1 receptors are cannabinoid receptors that are housed predominately in the brain and central nervous system. These play a large role in regulation of pain as their signaling function is utilized in various regulatory systems. Research indicates that these receptors have a large impact on executive functioning and suppressing synaptic transmissions. In basic terms, CB1 receptors help decide what signals are important enough to send to the brain. This means that signals like pain, hunger, and inflammation are all regulated by this system.

CB2 receptors are more widespread throughout the body. They are more present in the immune system and hematopoietic system (organs and tissues). They are also present in the brain and nervous system, but less so than CB1 receptors. CB2 receptors aid in immunological responses, including inflammation. The widespread characteristic of this receptor is indicative of its effect on far reaching neurological systems. Conditions happening throughout the entire body are more impacted by the regulation, or dysregulation, of these receptors. For example, CB2 receptors found in the digestive tract are suspected to be involved in chronic inflammatory conditions involving the gut.

CB1 receptors have been identified as heavily impacted by THC, the euphoric cannabinoid compound. This explains why THC works to mitigate pain symptoms and aid in pain management. CBD affects the entire endocannabinoid system, meaning that it works throughout the body in a number of different ways.

CBD has unlocked our knowledge and the potential of this intricate system.

There is a clear association between phytocannabinoids (cannabinoids from plants) and the endocannabinoid system, which bears a similar name. This is no coincidence, especially when you consider that the discovery of this regulatory system was a side effect of CBD research. The topic of current research is how CBD activates this system and allows the body to regulate itself better. CBD does not “cure” these ailments in and of itself. What is being seen and theorized is that cannabinoids work to activate receptors that might not be functioning the way they should. Research is currently being done on other animal species in which an endocannabinoid system has been identified.

Furthermore, cannabinoids are not only found in the cannabis plants. There are many other sources of this naturally occurring substance. Flax seeds, Echinacea, black pepper, and Maca are all examples of sources of phytocannabinoids, however none has been found to contain the volume that Cannabis and Hemp contain. This is especially exciting because it lends even more legitimacy to the research being done on cannabis and the endocannabinoid system.

If you are interested in trying CBD or just want more information about the endocannabinoid system, feel free to call Revexia anytime at (970) 449-1603, or stop by our storefront at 1724 Topaz Dr. in Loveland.

Cooking with CBD

Cooking with CBD

There are countless products on the market that are infused with cannabidiol, or CBD.

Head to your local gas station, and you will likely discover small treats infused with this cannabinoid. Although not technically legal because of lack of U.S. Food and Drug Administration (FDA) regulations, the commonplace of CBD snacks is incredible.

Countless people claim CBD ingestion has positively altered their lives. CBD is best known for its association with epilepsy, as people who suffer with rare forms of this condition are untreatable with pharmaceutical medication. The FDA has even patented a drug, called Epidiolex, which is the first cannabis-derived medication prescribed. In property, CBD has been claimed to be anti-inflammatory, reduce pain and anxiety, and has been touted as a sleep aid; the benefits are boundless.

Because of hemp’s recent removal from the schedule one drug listing, hemp-derived CBD is now federally legal. However, the FDA has not set forth an action plan to regulate CBD in food and beverages. Of all the CBD food and beverage products on the market, best practice is to always research the company to ensure you are purchasing organic, safe CBD.

Cooking with CBD

To resolve this issue, infusing your own tasty treats is simple, and you can be assured of exactly what you are ingesting. Here are a few tips for cooking with CBD, and below is one of our favorite recipes using CBD.

  • CBD binds to fat. Therefore, throw some extra oil or butter into your recipe so the CBD has the highest chance to stick around.
  • Never put CBD over direct heat and get it to a hot temperature. The chemical structure will break down and this cannabinoid will lose a lot of its effectiveness.
  • Storing your CBD-infused food is also something necessary to keep in mind. As CBD is extremely sensitive to heat and light, storing your food out of direct light and warmth will ensure the maximum potency.
  • Although mild in taste, when adding CBD to your recipe, be mindful there is an earthy flavor that is inescapable due to being derived from a plant.
  • To ensure CBD makes its way through the entirety of the dish, continuously stir your recipe.

People commonly infuse CBD into sweet treats to attempt to mask the earthy flavor. However, instead of covering up its innate taste, I figured I would embrace this earthiness. Since it is chilly out here during this Colorado winter, soups have been my go-to. By seamlessly adding CBD into my soup, I was able to stay warm and calm.

I give to you, CBD-infused cauliflower soup.

I made it vegan, but you don’t have to!

cauliflower soup with organic tincture


  • 3 tablespoons of olive oil
  • Head of cauliflower
  • 1 yellow onion
  • All the garlic your heart desires (I added 7 cloves)
  • 2 cups of vegetable broth
  • 1 cup of milk (I used oat milk)
  • 1 teaspoon of salt
  • 1 teaspoon of black pepper
  • 5 tablespoons of nutritional yeast
  • 2 stalks of green onion
  • Revexia’s RESTORE BALANCE Hemp Extract tincture
  1. Heat the olive oil in a deep pan, and add the chopped onion and garlic. Cook until the onions are translucent.
  2. Add the chopped cauliflower. Stir for 10 minutes, until the florets start getting some color.
  3. Add the vegetable broth and plant milk. Stir for 5 minutes, then set heat to low and cover. Let this sit for about 20 minutes.
  4. Add the salt, pepper, and nutritional yeast.
  5. Transfer to a blender. Blend until smooth.
  6. Transfer back to pan. The serving size is 5, and I wanted to achieve 5 milligrams of CBD per serving. Therefore I added 5 full droppers of Revexia’s RESTORE BALANCE Hemp Extract tincture. Stir.
  7. Garnish with green onion (which I regret not doing).
  8. Set up your favorite movie, because your night is about to get cozy and relaxing.

Visit our online store at https://revexia.life/shop/ to peruse our wide tincture range and check out the other CBD-infused goodies we have to offer. Give us a call anytime at (970) 449-1603 or stop into our storefront at 1724 Topaz Dr. in Loveland, Colorado.

Pro-tip: Add the Powderhemp Pure Hemp CBD Oil in spearmint flavor to your morning tea to have an anxiety and pain free day.